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Article

Endothelial nitric oxide synthase gene polymorphisms are associated with cardiovascular risks in prehypertensives.

Journal of the American Society of Hypertension : JASH - 1 Nov 2016

Pal Gopal Krushna, Adithan Chandrasekaran, Umamaheswaran Gurusamy, Pal Pravati, Nanda Nivedita, Indumathy Jagadeeswaran, Syamsunder Avupati Naga

Abstract excerpt

Though endothelial nitric oxide synthase (eNOS) gene polymorphism is documented in the causation of hypertension, its role in prehypertension has not been investigated. The present study was conducted in 172 subjects divided into prehypertensives (n = 57) and normotensives (n = 115). Cardiovascular (CV) parameters including baroreflex sensitivity (BRS) by continuous BP variability assessment and sympathovagal...

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PMID: 27697448
DOI: 10.1016/j.jash.2016.09.001

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