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Article

The BK channel β1 subunit gene is associated with human baroreflex and blood pressure regulation

1 May 2002

Abstract excerpt

BACKGROUND: The baroreflex, which is important for the minute-to-minute regulation of blood pressure and heart rate, is influenced by genetic variance. Ion channels are important to baroreflex afferent and efferent function. Mice missing the beta1 subunit of the Ca2+-sensitive potassium channel (BK) are hypertensive and have a reset baroreflex. We tested the hypothesis that variants in the gene (KCNMB1) coding...

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Share to Cardiac electrophysiology and arrhythmias
Share to Heart Rate Variability and Autonomic Control
Share to Ion channel regulation and function

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Identifiers

PMID: 12011654
DOI: 10.1097/00004872-200205000-00028

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