Dimeric Brucella abortus Irr protein controls its own expression and binds haem.

Abstract excerpt

Brucella abortus needs to synthesize haem in order to replicate intracellularly and to produce virulence in mice. Thus, to gain insight into the pathogenesis of the bacterium, regulatory proteins of the haem biosynthetic pathway were sought. An iron response regulator (Irr) from Bradyrhizobium japonicum, which is a close relative of Brucella, was previously described as being involved in the coordination of haem...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Brucella abortus
• Share to Cattle
• Share to Cloning, Molecular