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Article

The role of Dam methylation in phase variation of Haemophilus influenzae genes involved in defence against phage infection.

Microbiology (Reading, England) - 1 Oct 2005

Zaleski Piotr, Wojciechowski Marek, Piekarowicz Andrzej

Abstract excerpt

Haemophilus influenzae uses phase variation (PV) to modulate the activity of its defence systems against phage infection. The PV of the restriction-modification (R-M) system HindI, the main defence system against phage infection and incoming chromosomal and phage DNA in H. influenzae Rd, is driven by changes of the pentanucleotide repeat tract within the coding sequence of the hsdM gene and is influenced by lack...

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PMID: 16207918
DOI: 10.1099/mic.0.28184-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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