Article
Association between monoamine oxidase gene polymorphisms and smoking behaviour in Chinese males.
The international journal of neuropsychopharmacology - 1 Oct 2006
Jin Ying, Chen Dafang, Hu Yonghua, Guo Song, Sun Hongqiang, Lu Aili, Zhang Xiaoyan, Li Lingsong
Abstract excerpt
Monoamine oxidase (MAO) is a critical metabolic enzyme of dopamine, which is a key neurotransmitter of the mesolimbic reward pathway in the human brain. Consequently, the gene encoding MAO is an important candidate gene in the genetics of smoking behaviour. We investigated the association between MAOA polymorphisms (a VNTR polymorphism and an EcoRV polymorphism) and smoking status. A community-based...
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