Article
Monoamine oxidase polymorphisms and smoking behaviour in Japanese.
Pharmacogenetics - 1 Feb 2003
Ito Hidemi, Hamajima Nobuyuki, Matsuo Keitaro, Okuma Katashi, Sato Sigeki, Ueda Ryuzo, Tajima Kazuo
Abstract excerpt
Although nicotine dependence is one of the primary reasons why smokers cannot quit smoking, nicotine cannot explain all of the psychopharmacological effects of tobacco smoke. Accumulating evidence points to potent inhibition of monoamine oxidase (MAO) which metabolizes neurotransmitters relating to additive behaviour. We have therefore investigated the association between smoking behaviour and MAO ( variable...
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