Article
Extension of the DNA binding consensus of the chicken c-Myb and v-Myb proteins.
Nucleic acids research - 25 Jun 1992
Weston K
Abstract excerpt
The chicken c-myb gene and the v-myb oncogene transduced by avian myeloblastosis virus (AMV) encode DNA binding transcription activators. The DNA binding domain of AMV v-Myb displays a number of amino acid changes relative to c-Myb; v-Myb proteins in which one or more of three crucial residues in the DNA binding domain are mutated to resemble the c-Myb sequence display altered transformation phenotypes. In order...
Topics
- Amino Acid Sequence
- Animals
- Avian Myeloblastosis Virus
- Base Sequence
- Binding Sites
- Chickens
- Consensus Sequence
- DNA-Binding Proteins
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides