Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between hormonal signaling pathways in Drosophila melanogaster as revealed by genetic interaction between methoprene-tolerant and broad-complex.

Genetics - 1 Jan 2006

Wilson Thomas G, Yerushalmi Yoram, Donnell David M, Restifo Linda L

Abstract excerpt

Juvenile hormone (JH) regulates insect development by a poorly understood mechanism. Application of JH agonist insecticides to Drosophila melanogaster during the ecdysone-driven onset of metamorphosis results in lethality and specific morphogenetic defects, some of which resemble those in mutants of the ecdysone-regulated Broad-Complex (BR-C). The Methoprene-tolerant (Met) bHLH-PAS gene mediates JH action, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Basic Helix-Loop-Helix Transcription Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Survival

Share to Insecticide Resistance

Share to Metamorphosis, Biological

Share to Oogenesis

Share to Zinc Fingers

Source

Open in PubMed Open full text

Identifiers

PMID: 16204218
DOI: 10.1534/genetics.105.046631
PMCID: PMC1456152

Genes

MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between hormonal signaling pathways in Drosophila melanogaster as revealed by genetic interaction between methoprene-tolerant and broad-complex.PMID 16204218Read ↗

A juvenile hormone agonist reveals distinct developmental pathways mediated by ecdysone-inducible broad complex transcription factors.Semantic proximity Read ↗

Wide mutational spectrum of a gene involved in hormone action and insecticide resistance in Drosophila melanogaster.Semantic proximity Read ↗

Drosophila Met and Gce are partially redundant in transducing juvenile hormone action.Semantic proximity Read ↗

The ecdysone-inducible Broad-complex and E74 early genes interact to regulate target gene transcription and Drosophila metamorphosis.Semantic proximity Read ↗

Relationships between protein isoforms and genetic functions demonstrate functional redundancy at the Broad-Complex during Drosophila metamorphosis.Semantic proximity Read ↗

Anciently duplicated Broad Complex exons have distinct temporal functions during tissue morphogenesis.Semantic proximity Read ↗

The Drosophila Broad-Complex plays a key role in controlling ecdysone-regulated gene expression at the onset of metamorphosis.Semantic proximity Read ↗

Juvenile hormone involvement in Drosophila melanogaster male reproduction as suggested by the Methoprene-tolerant(27) mutant phenotype.Semantic proximity Read ↗

Pleiotropic effects of methoprene-tolerant (Met), a gene involved in juvenile hormone metabolism, on life history traits in Drosophila melanogaster.Semantic proximity Read ↗

Downregulation of the tissue-specific transcription factor Fork head by Broad-Complex mediates a stage-specific hormone response.Semantic proximity Read ↗

Mutations in a steroid hormone-regulated gene disrupt the metamorphosis of the central nervous system in Drosophila.Semantic proximity Read ↗

Molecular analysis of the Methoprene-tolerant gene region of Drosophila melanogaster.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.