Article
Multiple human papillomavirus genes affect the adeno-associated virus life cycle.
Virology - 20 Jan 2006
You Hong, Liu Yong, Prasad C Krishna, Agrawal Nalini, Zhang Dazhi, Bandyopadhyay Sarmistha, Liu Hongmei, Kay Helen H, Mehta Jawahar L, Hermonat Paul L
Abstract excerpt
The risk of cervical cancer, one of the most prevalent cancers in the world, is determined by two viruses. Human papillomavirus (HPV) is the main risk factor for developing cervical cancer. However, although little known, it is well substantiated that the human Parvovirus adeno-associated virus type 2 (AAV), and its encoded Rep78 protein, interacts with HPV and lowers the risk of cervical cancer. HPV also...
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