Transcription of the gene for a pepsinogen, PEP1, is regulated by white-opaque switching in Candida albicans.

doi:10.1128/mcb.12.7.2997

Article

Transcription of the gene for a pepsinogen, PEP1, is regulated by white-opaque switching in Candida albicans.

1 Jul 1992

Abstract excerpt

Cells of Candida albicans WO-1 spontaneously switch between a white and opaque CFU, and this phase transition involves a dramatic change in cellular phenotype. By using a differential hybridization screen, an opaque-specific cDNA, Op1a, which represents the transcript of a gene regulated by switching, has been isolated. The gene for Op1a is transcribed by opaque but not by white cells. The nucleotide sequence of...

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