Article
A review of the MHC genetics of rheumatoid arthritis.
Genes and immunity - 1 May 2004
Newton J L, Harney S M J, Wordsworth B P, Brown M A
Abstract excerpt
Rheumatoid arthritis is a common complex genetic disease, and, despite a significant genetic element, no gene other than HLA-DRB1 has been clearly demonstrated to be involved in the disease. However, this association accounts for less than half the overall genetic susceptibility. Investigation of other candidate genes, in particular those that reside within the major histocompatibility complex, are hampered by...
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