Article
Concomitant neutrophil <i>JAK2</i><sup>V617F</sup> mutation screening and <i>PRV‐1</i> expression analysis in myeloproliferative disorders and secondary polycythaemia
6 Sept 2005
Abstract excerpt
Polycythaemia vera (PV) is closely associated with both an acquired activating mutation of the JAK2 tyrosine kinase (JAK2(V617F)) in granulocyte-derived DNA and increased granulocyte polycythaemia rubra vera-1 (PRV-1) expression. In order to explore the correlation between these two biological markers and compare their diagnostic utility, mutation analysis for JAK2(V617F) and quantitative measurement of...
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