Article
Constitutive neuronal expression of CCR2 chemokine receptor and its colocalization with neurotransmitters in normal rat brain: functional effect of MCP-1/CCL2 on calcium mobilization in primary cultured neurons.
The Journal of comparative neurology - 14 Nov 2005
Banisadr Ghazal, Gosselin Romain-Daniel, Mechighel Patricia, Rostène William, Kitabgi Patrick, Mélik Parsadaniantz Stéphane
Abstract excerpt
Chemokines and their receptors are well described in the immune system, where they promote cell migration and activation. In the central nervous system, chemokine has been implicated in neuroinflammatory processes. However, an increasing number of evidence suggests that they have regulatory functions in the normal nervous system, where they could participate in cell communication. In this work, using a...
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