Article
Extreme individual marker F(ST )values do not imply population-specific selection in humans: the NRG1 example.
Human genetics - 1 Jul 2007
Gardner Michelle, Williamson Scott, Casals Ferran, Bosch Elena, Navarro Arcadi, Calafell Francesc, Bertranpetit Jaume, Comas David
Abstract excerpt
Extreme population differentiation, as measured by the F(ST) value, has been suggested as an indicator of recent population-specific positive selection. Elevated F(ST) values indicating high differentiation between continental groups were previously reported on a linkage disequilibrium region in the Neuregulin 1 gene, a gene which has been associated to schizophrenia. In the present study we show evidence that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.