Article
A systems biology approach for the study of cumulative oncogenes with applications to the MAPK signal transduction pathway.
Biophysical chemistry - 1 Jan 2006
Pant Dhruv K, Ghosh Avijit
Abstract excerpt
The Extracellular signal Regulated Kinase (ERK) pathway is one of the most well-studied signaling pathways in cell cycle regulation. Disruption in the normal functioning of this pathway is linked to many forms of cancer. In a previous study [D.K. Pant, A. Ghosh, Automated oncogene detection in complex protein networks, with applications to the MAPK signal transduction pathway, Biophys. Chem. 113 (2005) 275-288.],...
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