Article
Genetic diversity of KIR natural killer cell markers in populations from France, Guadeloupe, Finland, Senegal and Réunion.
Tissue antigens - 1 Oct 2005
Denis L, Sivula J, Gourraud P-A, Kerdudou N, Chout R, Ricard C, Moisan J-P, Gagne K, Partanen J, Bignon J-D
Abstract excerpt
Killer cell immunoglobulin-like receptors (KIRs) belong to a diverse family of natural killer (NK) cell receptors recognizing human leukocyte antigen (HLA) class I molecules. Due to this functional link, KIR molecules are expected to display a high polymorphism, such as their HLA ligands. Moreover, many studies conducted in mouse and human models have shown that NK-KIR receptors play an important role in...
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