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Article

Splenic marginal zone B cells in humans: where do they mutate their Ig receptor?

European journal of immunology - 1 Oct 2005

Weller Sandra, Reynaud Claude-Agnès, Weill Jean-Claude

Abstract excerpt

Human IgM+ IgD+ CD27+ B cells have mutated Ig genes and harbor a splenic marginal zone (MZ) phenotype. In this issue, the group of R. Küppers has studied the expression of the enzyme activation-induced cytidine deaminase (AID) in human spleen samples by immunocytochemistry and failed to detect a significant AID-expressing subset in the MZ region. The consequences on the possible origin of these cells are discussed.

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Source

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Identifiers

PMID: 16180256
DOI: 10.1002/eji.200535446
PMCID: PMC2694967

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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