Article
Association of transforming growth factor-beta1 single nucleotide polymorphism C-509T with allergy and immunological activities.
International archives of allergy and immunology - 1 Oct 2005
Meng Jianfeng, Thongngarm Torpong, Nakajima Mikio, Yamashita Naomi, Ohta Ken, Bates Christopher A, Grunwald Gary K, Rosenwasser Lanny J
Abstract excerpt
BACKGROUND: A single nucleotide polymorphism (SNP) C-509T within the tumor growth factor beta1 (TGFbeta1) gene has been associated with atopic asthma and asthma severity. To further understand the mechanisms involved, the association of C-509T with allergy, T-lymphocyte proliferation and plasma TGFbeta1 concentration has been explored in a case-control study with allergic and non-allergic subjects. METHODS: The...
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