Article
Prevalence of HFE (hemochromatosis) gene mutations in patients with cluster headache.
Headache - 1 Oct 2005
Rainero Innocenzo, Rivoiro Chiara, Rubino Elisa, Milli Valentina, Valfrè Walter, De Martino Paola, Lo Giudice Rossana, Angilella Giuseppina, Savi Lidia, Gallone Salvatore, Pinessi Lorenzo
Abstract excerpt
OBJECTIVE: To evaluate whether polymorphisms of the HFE gene would modify the occurrence and the clinical features of cluster headache (CH). BACKGROUND: Recent studies suggested that iron metabolism may be involved in the pathophysiology of primary headaches. The HFE gene encodes for a protein that modulates iron absorption. Mutations in this gene are responsible for toxic iron overload in several body organs....
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