Th1 cytokines are essential for placental immunity to Listeria monocytogenes.

doi:10.1128/IAI.73.10.6322-6331.2005

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Article

Th1 cytokines are essential for placental immunity to Listeria monocytogenes.

Infection and immunity - 1 Oct 2005

Barber Ellen M, Fazzari Melissa, Pollard Jeffrey W

Abstract excerpt

The fetal allograft poses an immunological challenge: how is it protected while immunity to pathogens, particularly those that replicate in the placenta, is maintained? Several theories have been proposed to explain this fetal protection, including a pregnancy-based bias towards a Th2 rather than Th1 cytokine profile in order to avoid generating cytotoxic T cells that could threaten the fetus. Listeria...

Topics

Animals
Cytokines
Female
Interferon-gamma
Listeria monocytogenes
Listeriosis
Mice
Mice, Mutant Strains
Mutation
Neutrophils
Placenta
Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pregnancy Complications, Infectious

Receptors, Tumor Necrosis Factor

Receptors, Tumor Necrosis Factor, Type I

Signal Transduction

Th1 Cells

Tumor Necrosis Factor Decoy Receptors

Source

Open in PubMed Open full text

Identifiers

PMID: 16177303
DOI: 10.1128/IAI.73.10.6322-6331.2005
PMCID: PMC1230899

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