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Article

Concurrence of Plasmodium falciparum dhfr and crt mutations in northern Ghana.

Malaria journal - 15 Sept 2005

Mockenhaupt Frank P, Bousema J Teun, Eggelte Teunis A, Ehrhardt Stephan, Otchwemah Rowland N, Sauerwein Robert W, Bienzle Ulrich

Abstract excerpt

BACKGROUND: Both chloroquine (CQ) and sulfadoxine-pyrimethamine (SP) are failing drugs in much of sub-Saharan Africa. Previous findings suggest an association between resistance to CQ and to SP in vivo, in vitro, and on the molecular level. METHODS: In 126 Ghanaian children with uncomplicated malaria, associations between mutations conferring resistance in the Plasmodium falciparum dihydrofolate reductase (dhfr;...

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Identifiers

PMID: 16164748
DOI: 10.1186/1475-2875-4-42
PMCID: PMC1261531

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Source receipt: pubmed, retrieved 7 Sept 2026.

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