Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for recent positive selection at the human AIM1 locus in a European population.

Molecular biology and evolution - 1 Jan 2006

Soejima Mikiko, Tachida Hidenori, Ishida Takafumi, Sano Akinori, Koda Yoshiro

Abstract excerpt

Two missense polymorphisms (E272K and L374F) of the AIM1 locus, encoding a melanocyte differentiation antigen, were shown to have a clear association with human ethnicities. These two nonpathogenic single nucleotide polymorphisms (SNPs) may be associated with human pigmentation variation. In this study, we investigated sequence variation in the coding region and exon-flanking sequence and found low genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, High Pressure Liquid
Share to Crystallins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Europe

Share to Pigmentation

Share to Polymorphism, Restriction Fragment Length

Share to Selection, Genetic

Share to White People

Source

Identifiers

PMID: 16162863
DOI: 10.1093/molbev/msj018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for recent positive selection at the human AIM1 locus in a European population.PMID 16162863Read ↗

Signatures of positive selection in genes associated with human skin pigmentation as revealed from analyses of single nucleotide polymorphisms.Semantic proximity Read ↗

Distinctive distribution of AIM1 polymorphism among major human populations with different skin color.Semantic proximity Read ↗

Exploring signatures of positive selection in pigmentation candidate genes in populations of East Asian ancestry.Semantic proximity Read ↗

Dissecting dynamics and differences of selective pressures in the evolution of human pigmentation.Semantic proximity Read ↗

Positive selection in Europeans and East-Asians at the <i>ABCA12</i> geneSemantic proximity Read ↗

Simultaneous purifying selection on the ancestral MC1R allele and positive selection on the melanoma-risk allele V60L in south Europeans.Semantic proximity Read ↗

Dissecting dynamics and differences of selective pressures in the evolution of human pigmentationSemantic proximity Read ↗

Evidence for positive selection on a number of MicroRNA regulatory interactions during recent human evolution.Semantic proximity Read ↗

OPRM1 and EGFR contribute to skin pigmentation differences between Indigenous Americans and Europeans.Semantic proximity Read ↗

A Scan for Signatures of Positive Selection in Candidate Loci for Skin Pigmentation in HumansSemantic proximity Read ↗

Haplotype differences for copy number variants in the 22q11.23 region among human populations: a pigmentation-based model for selective pressure.Semantic proximity Read ↗

Direct evidence for positive selection of skin, hair, and eye pigmentation in Europeans during the last 5,000 y.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.