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Article

Exploring signatures of positive selection in pigmentation candidate genes in populations of East Asian ancestry.

BMC evolutionary biology - 12 Jul 2013

Hider Jessica L, Gittelman Rachel M, Shah Tapan, Edwards Melissa, Rosenbloom Arnold, Akey Joshua M, Parra Esteban J

Abstract excerpt

BACKGROUND: Currently, there is very limited knowledge about the genes involved in normal pigmentation variation in East Asian populations. We carried out a genome-wide scan of signatures of positive selection using the 1000 Genomes Phase I dataset, in order to identify pigmentation genes showing putative signatures of selective sweeps in East Asia. We applied a broad range of methods to detect signatures of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23848512
DOI: 10.1186/1471-2148-13-150
PMCID: PMC3727976

Genes

BNC2
EGFR
LYST
OCA2
OPRM1
PMEL
TYRP1
ADAM17
ATRN
CTSD
DCT
EDAR
KLHL7
MITF
MLPH
PDIA6
TMEM33
TRPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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