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Article

Human sulphotransferases are involved in the activation of aristolochic acids and are expressed in renal target tissue

20 Dec 2005

Abstract excerpt

Use of herbal preparations containing Aristolochia species has led to progressive nephropathy and urothelial cancer in humans. Analysis of DNA adducts formed in human target tissues and studies in animal models have pointed out a major role of the secondary plant metabolites, aristolochic acids, in these effects. Only a minority of the users of Aristolochia-containing products developed nephropathy and cancer,...

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PMID: 16161050
DOI: 10.1002/ijc.21480

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Human sulphotransferases are involved in the activation of aristolochic acids and are expressed in renal target tissuePMID 16161050Read ↗

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