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Article

Design of long oligonucleotide probes for functional gene detection in a microbial community.

Bioinformatics (Oxford, England) - 15 Nov 2005

Chung Won-Hyong, Rhee Sung-Keun, Wan Xiu-Feng, Bae Jin-Woo, Quan Zhe-Xue, Park Yong-Ha

Abstract excerpt

MOTIVATION: Analysis of the functions of microorganisms and their dynamics in the environment is essential for understanding microbial ecology. For analysis of highly similar sequences of a functional gene family using microarrays, the previous long oligonucleotide probe design strategies have not been useful in generating probes. RESULTS: We developed a Hierarchical Probe Design (HPD) program that designs both...

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PMID: 16159916
DOI: 10.1093/bioinformatics/bti673

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HPD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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