Article
Detecting variants with Metabolic Design, a new software tool to design probes for explorative functional DNA microarray development.
BMC bioinformatics - 23 Sept 2010
Terrat Sébastien, Peyretaillade Eric, Gonçalves Olivier, Dugat-Bony Eric, Gravelat Fabrice, Moné Anne, Biderre-Petit Corinne, Boucher Delphine, Troquet Julien, Peyret Pierre
Abstract excerpt
BACKGROUND: Microorganisms display vast diversity, and each one has its own set of genes, cell components and metabolic reactions. To assess their huge unexploited metabolic potential in different ecosystems, we need high throughput tools, such as functional microarrays, that allow the simultaneous analysis of thousands of genes. However, most classical functional microarrays use specific probes that monitor only...
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