Glutamic acid decarboxylase autoantibody prevalence and association with HLA genotype in patients with younger-onset type 1 diabetes and proliferative diabetic retinopathy.

Abstract excerpt

OBJECTIVE: To investigate the relationship of HLA status and autoantibodies to glutamic acid decarboxylase (GAD) in proliferative diabetic retinopathy (PDR) to assess the role of autoimmunity and genetic markers in retinopathy. DESIGN: Retrospective, nonrandomized, comparative study. PARTICIPANTS: Patients who had suffered from type 1 diabetes for >10 years and who had been first diagnosed as diabetic under 30...

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