Article
A novel polymorphism A(+884)-->G in the hepatic lipase gene and its association with coronary artery disease.
Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica - 1 Jul 2003
Su Zhi-Guang, Zhang Si-Zhong, Zhang Li, Tong Yu, Xiao Cui-Ying, Hou Yi-Ping, Liao Lin-Chuan
Abstract excerpt
Hepatic lipase (HL) activity may influence susceptibility to coronary artery disease (CAD). Association between the single nucleotide polymorphisms (SNPs) in the HL gene with the occurrence of CAD has been investigated thoroughly, but to date most studies focused on the base variation in the promoter of HL gene, little is known about the variation in the coding region. In present study, the SNP in all exons of...
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