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Article

A novel allele in the promoter of the hepatic lipase is associated with increased concentration of HDL-C and decreased promoter activity.

Journal of lipid research - 1 Oct 2002

Su Zhiguang, Zhang Sizhong, Nebert Daniel W, Zhang Li, Huang Dejia, Hou Yiping, Liao Linchuan, Xiao Cuiying

Abstract excerpt

Hepatic lipase (HL) is a lipolytic enzyme involved in the metabolism of plasma lipoproteins, especially HDLs. Association of the polymorphisms in the promoter region of the LIPC gene to post-heparin plasma HL activity and the plasma HDL-C concentration has been investigated thoroughly, but to date little is known about this in the Chinese. In the present study, we analyzed the polymorphisms in the promoter region...

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Source

Identifiers

PMID: 12364543
DOI: 10.1194/jlr.m200046-jlr200

Genes

CAD
LIPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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