Article
A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility.
Proceedings of the National Academy of Sciences of the United States of America - 13 Sept 2005
Shepard Jennifer L, Amatruda James F, Stern Howard M, Subramanian Aravind, Finkelstein David, Ziai James, Finley K Rose, Pfaff Kathleen L, Hersey Candace, Zhou Yi, Barut Bruce, Freedman Matthew, Lee Charles, Spitsbergen Jan, Neuberg Donna, Weber Gerhard, Golub Todd R, Glickman Jonathan N, Kutok Jeffery L, Aster Jon C, Zon Leonard I
Abstract excerpt
A major goal of cancer research has been to identify genes that contribute to cancer formation. The similar pathology between zebrafish and human tumors, as well as the past success of large-scale genetic screens in uncovering human disease genes, makes zebrafish an ideal system in which to find...
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