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Article

Lung development is not necessary for diaphragm development in mice.

Journal of pediatric surgery - 1 Sept 2005

Arkovitz Marc S, Hyatt Brian A, Shannon John M

Abstract excerpt

BACKGROUND/PURPOSE: Congenital diaphragmatic hernia affects approximately 1 in every 2000 live births. The etiology of these diaphragmatic defects is unknown. Using mice with a targeted deletion of fibroblast growth factor 10 (FGF10), which display a complete lack of lung tissue, we have examined the relationship between lung hypoplasia and diaphragmatic development. METHODS: The diaphragms of FGF10 null mice...

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Source

Identifiers

PMID: 16150338
DOI: 10.1016/j.jpedsurg.2005.05.059

Genes

FGF10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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