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Article

MicroRNA-200b regulates distal airway development by maintaining epithelial integrity

19 Jul 2017

Abstract excerpt

Abstract miR-200b plays a role in epithelial-to-mesenchymal transition (EMT) in cancer. We recently reported abnormal expression of miR-200b in the context of human pulmonary hypoplasia in congenital diaphragmatic hernia (CDH). Smaller lung size, a lower number of airway generations, and a thicker mesenchyme characterize pulmonary hypoplasia in CDH. The aim of this study was to define the role of miR-200b during...

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Share to Congenital Anomalies and Fetal Surgery
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PMID: 28743913
DOI: 10.1038/s41598-017-05412-y

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