Article
[Hereditary skeletal dysplasias and FGFR3 and PTHR1 signaling pathways].
Medecine sciences : M/S - 1 Nov 2005
Bonaventure Jacky, Silve Caroline
Abstract excerpt
Skeletal development is a highly sophisticated process involving, as a first step, migration and condensation of mesenchymal cells into osteoprogenitor cells. These cells further differentiate into chondrocytes and osteoblasts through multiple differentiation stages requiring a set of specific transcriptional factors. Defective endochondral ossification in human is associated with a large number of inherited...
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