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Germline genetic variants with implications for disease risk and therapeutic outcomes.

Physiological genomics - 1 Oct 2017

Pasternak Amy L, Ward Kristen M, Luzum Jasmine A, Ellingrod Vicki L, Hertz Daniel L

Abstract excerpt

Genetic testing has multiple clinical applications including disease risk assessment, diagnosis, and pharmacogenomics. Pharmacogenomics can be utilized to predict whether a pharmacologic therapy will be effective or to identify patients at risk for treatment-related toxicity. Although genetic tests are typically ordered for a distinct clinical purpose, the genetic variants that are found may have additional...

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Identifiers

PMID: 28887371
DOI: 10.1152/physiolgenomics.00035.2017
PMCID: PMC5668651

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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