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Article

Biochemical characterization and crystal structure of a Dim1 family associated protein: Dim2.

Biochemistry - 13 Sept 2005

Simeoni Federica, Arvai Andy, Bello Paul, Gondeau Claire, Hopfner Karl-Peter, Neyroz Paolo, Heitz Frederic, Tainer John, Divita Gilles

Abstract excerpt

The U4/U6*U5 tri-snRNP complex is the catalytic core of the pre-mRNA splicing machinery. The thioredoxin-like protein hDim1 (U5-15 kDa) constitutes an essential component of the U5 particle, and its functions have been reported to be highly conserved throughout evolution. Recently, the Dim1-like protein (DLP) family has been extended to other proteins harboring similar sequence motifs. Here we report the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16142897
DOI: 10.1021/bi050427o

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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