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Article

RNA polymerase IV directs silencing of endogenous DNA.

Science (New York, N.Y.) - 1 Apr 2005

Herr A J, Jensen M B, Dalmay T, Baulcombe D C

Abstract excerpt

Plants encode subunits for a fourth RNA polymerase (Pol IV) in addition to the well-known DNA-dependent RNA polymerases I, II, and III. By mutation of the two largest subunits (NRPD1a and NRPD2), we show that Pol IV silences certain transposons and repetitive DNA in a short interfering RNA pathway involving RNA-dependent RNA polymerase 2 and Dicer-like 3. The existence of this distinct silencing polymerase may...

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Source

Identifiers

PMID: 15692015
DOI: 10.1126/science.1106910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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RNA polymerase IV directs silencing of endogenous DNA.PMID 15692015Read ↗

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