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Article

Kinetic comparison of procaspase-3 and caspase-3.

Archives of biochemistry and biophysics - 1 Oct 2005

Karki Pratap, Lee Jungsup, Shin Song Yub, Cho Byungyun, Park Il-Seon

Abstract excerpt

Caspases, the key enzymes in apoptosis, are synthesized as proenzymes and converted into active form by proteolytic cleavage. The residues on active site reorganize during the activation process as shown in the comparative studies of crystallographic structures of procaspase-7 and its mature form. On the other hand, the proenzyme itself has some activity. Aiming to characterize the activation process, the...

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Identifiers

PMID: 16140256
DOI: 10.1016/j.abb.2005.07.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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