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Article

Reassembly of active caspase-3 is facilitated by the propeptide.

The Journal of biological chemistry - 2 Dec 2005

Feeney Brett, Clark A Clay

Abstract excerpt

Changes in ionic homeostasis are early events leading up to the commitment to apoptosis. Although the direct effects of cations on caspase-3 activity have been examined, comparable studies on procaspase-3 are lacking. In addition, the effects of salts on caspase structure have not been examined. We have studied the effects of cations on the activities and conformations of caspase-3 and an uncleavable mutant of...

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Identifiers

PMID: 16203739
DOI: 10.1074/jbc.M505834200
PMCID: PMC3119714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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