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Article

A new and simple approach for genotyping Alzheimer's disease presenilin-1 mutant knock-in mice.

Journal of neuroscience methods - 30 Jul 2009

Gautheron Vanessa, Auffret Alexandra, Mattson Mark P, Mariani Jean, Vernet-der Garabedian Béatrice

Abstract excerpt

The use of transgenic mice expressing point mutations demands that the detection of the different alleles is efficient and reliable. In addition, the multiplication of transgenes included in mouse models of human disease underlines the importance of correct controls and the fact that investigators need an accurate and rapid genotyping of the littermates generated. In this study, we demonstrate a powerful...

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Identifiers

PMID: 19465058
DOI: 10.1016/j.jneumeth.2009.05.009
PMCID: PMC2789286

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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