Article
[No association between catechol-O-methyltransferase val158met polymorphism and alexithymia].
Zeitschrift fur Psychosomatische Medizin und Psychotherapie - 1 Jan 2011
Hermes Sandra, Hennig Jürgen, Stingl Markus, Leichsenring Falk, Leweke Frank
Abstract excerpt
OBJECTIVES: Reduced concentrations of dopamine in prefrontal brain structures may play a role in alexithymia. Dopamine degradation in the orbitofrontal cortex is regulated by catechol-O-methyltransferase (COMT), and a functional single nucleotide polymorphism of the COMT gene, Val158Met, has been related to psychiatric illness. This study examines the association between the COMT Val158Met gene polymorphism, and...
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