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Article

Intensive therapy with ceftobiprole medocaril of experimental foreign-body infection by methicillin-resistant Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Sept 2005

Vaudaux Pierre, Gjinovci Asllan, Bento Manuela, Li Dongmei, Schrenzel Jacques, Lew Daniel P

Abstract excerpt

The therapeutic activity of ceftobiprole medocaril, the water-soluble prodrug of ceftobiprole, was compared to that of vancomycin in a rat tissue cage model of chronic methicillin-resistant Staphylococcus aureus (MRSA) foreign-body infection. The MICs and MBCs of ceftobiprole and vancomycin in Mueller-Hinton broth for strain MRGR3 were 1 and 4 and 1 and 2 microg/ml, respectively. In vitro elimination rates of...

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Identifiers

PMID: 16127054
DOI: 10.1128/AAC.49.9.3789-3793.2005
PMCID: PMC1195398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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