Article
Ceftobiprole efficacy in vitro against Panton-Valentine leukocidin production and in vivo against community-associated methicillin-resistant Staphylococcus aureus osteomyelitis in rabbits.
Antimicrobial agents and chemotherapy - 1 Dec 2012
Saleh-Mghir Azzam, Dumitrescu Oana, Dinh Aurélien, Boutrad Yassine, Massias Laurent, Martin Emilie, Vandenesch François, Etienne Jérôme, Lina Gérard, Crémieux Anne Claude
Abstract excerpt
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) can cause osteomyelitis with severe sepsis and/or local complications in which a Panton-Valentine leukocidin (PVL) role is suspected. In vitro sub-MIC antibiotic effects on growth and PVL production by 11 PVL(+) MRSA strai...
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