Linkage mapping of the carbonyl reductase (CBR) gene on human chromosome 21 using a DNA polymorphism in the 3' untranslated region.

doi:10.1016/0888-7543(92)90268-w

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Article

Linkage mapping of the carbonyl reductase (CBR) gene on human chromosome 21 using a DNA polymorphism in the 3' untranslated region.

Genomics - 1 Jun 1992

Avramopoulos D, Cox T, Forrest G L, Chakravarti A, Antonarakis S E

Abstract excerpt

A DNA polymorphism has been found in the 3' untranslated region of the carbonyl reductase gene (CBR). Genotypes of the members of the CEPH pedigrees have been obtained and used in linkage analysis to map the CBR gene in the linkage map of human chromosome 21. The gene maps between the interferon-...

Topics

Alcohol Oxidoreductases
Aldehyde Reductase
Aldo-Keto Reductases
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 21
DNA Mutational Analysis
Genes
Genotype
Humans
Lod Score
Molecular Sequence Data
Nucleic Acid Conformation
Polymerase Chain Reaction
Polymorphism, Genetic

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Open in PubMed

Identifiers

PMID: 1612603
DOI: 10.1016/0888-7543(92)90268-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1612603-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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