Article
Tetraploidy and chromosomal instability are early events during cervical carcinogenesis.
Carcinogenesis - 1 Feb 2006
Olaharski Andrew J, Sotelo Rita, Solorza-Luna Gilberto, Gonsebatt Maria E, Guzman Patricia, Mohar Alejandro, Eastmond David A
Abstract excerpt
Chromosomal instability as manifested by increases in aneuploidy and structural chromosome aberrations is believed to play a critical role in the intermediate to late stages in the development of cervical malignancies. The current study was designed to determine the role of tetraploidy in the formation of aneuploidy and ascertain the occurrence of these alterations during the earlier stages of cervical...
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