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Article

Modifying effects of the R389G beta1-adrenoceptor polymorphism on resting heart rate and blood pressure in patients with obstructive sleep apnoea.

Clinical science (London, England : 1979) - 1 Jan 2006

Börgel Jan, Schulz Tino, Bartels Nina K, Epplen Jörg T, Büchner Nikolaus, Rump Lars Christian, Huesing Anika, Sanner Bernd M, Mügge Andreas

Abstract excerpt

OSA (obstructive sleep apnoea) stimulates sympathetic nervous activity and elevates resting HR (heart rate) and BP (blood pressure). In the present study in a cohort of 309 untreated OSA patients, the resting HR and BP during the daytime were correlated with AHI (apnoea/hypopnea index) and compared with patients with R389R (n = 162), R389G (n = 125) and G389G (n = 22) genotypes of the beta1-adrenoreceptor R389G...

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Identifiers

PMID: 16122377
DOI: 10.1042/CS20050244

Genes

CPAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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