Article
Structural insights into the cellular retinaldehyde-binding protein (CRALBP).
Proteins - 1 Nov 2005
Liu Tianyun, Jenwitheesuk Ekachai, Teller David C, Samudrala Ram
Abstract excerpt
Cellular retinaldehyde-binding protein (CRALBP) is an essential protein in the human visual cycle without a known three-dimensional structure. Previous studies associate retinal pathologies to specific mutations in the CRALBP protein. Here we use homology modeling and molecular dynamics methods to investigate the structural mechanisms by which CRALBP functions in the visual cycle. We have constructed two...
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