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Article

Integrating biological regulatory network analysis and structural bioinformatics to probe CABP4 transcriptional regulation in night blindness.

Journal of biomolecular structure & dynamics - 1 Jul 2026

Fatima Sana, Amjad Zoya, Hashmi Mahnoor, Jabeen Ishrat

Abstract excerpt

The focus of this study is to exploit the role of calcium-binding protein 4 (CABP4) and calcium Ca2+ levels in the regulation of the Cav1.4 channel in rod photoreceptors. Moreover, It also examines the changes in the regulation that contribute to the development of night blindness. A biological regulatory network (BRN) model was developed, to simulate CABP4 regulation under varying Ca2+ levels as in normal and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40975890
DOI: 10.1080/07391102.2025.2562134

Genes

CABP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Integrating biological regulatory network analysis and structural bioinformatics to probe CABP4 transcriptional regulation in night blindness.PMID 40975890Read ↗

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