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Article

Clinical efficacy of fluvoxamine and functional polymorphism in a serotonin transporter gene on childhood autism.

Journal of autism and developmental disorders - 1 Jun 2005

Sugie Yoko, Sugie Hideo, Fukuda Tokiko, Ito Masataka, Sasada Yumiko, Nakabayashi Mutsumi, Fukashiro Kazunobu, Ohzeki Takehiko

Abstract excerpt

We studied the correlation between response to fluvoxamine and serotonin transporter gene promoter region polymorphism (5-HTTLPR). Eighteen children with autistic disorder completed a 12-week double-blind, placebo-controlled, randomized crossover study of fluvoxamine. Behavioral assessments were obtained before and at 12 weeks of treatment. 5-HTTLPR (long (l) or short(s)), was analyzed by the PCR method. Ten out...

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Source

Identifiers

PMID: 16119478
DOI: 10.1007/s10803-005-3305-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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