Article
Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice.
Blood - 15 Dec 2005
Eliopoulos Nicoletta, Stagg John, Lejeune Laurence, Pommey Sandra, Galipeau Jacques
Abstract excerpt
It has been suggested that marrow stromal cells (MSCs) may be immunoprivileged and can engraft in allogeneic recipients with intact immune systems. We determined if the implantation of murine MSCs engineered to release erythropoietin (Epo) would be feasible in major histocompatibility complex (MHC)-mismatched allogeneic mice without immunosuppression, and we monitored hematocrit (Hct) as a reporter of MSC graft...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
