Article
P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2005
Paredes Joana, Albergaria André, Oliveira João T, Jerónimo Carmen, Milanezi Fernanda, Schmitt Fernando C
Abstract excerpt
PURPOSE: P-cadherin overexpression has been reported in breast carcinomas, where it was associated with proliferative high-grade histological tumors. This study aimed to analyze P-cadherin expression in invasive breast cancer and to correlate it with tumor markers, pathologic features, and patient survival. Another purpose was to evaluate the P-cadherin promoter methylation pattern as the molecular mechanism...
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